Gonorrhoea in the chimpanzee. Serological testing.

This laboratory, with a special interest in the serodiagnosis of gonorrhoea, has become active in all aspects of serological testing of animal models as well as humans. Lucas, Chandler, Martin, and Schmale (1971) established the chimpanzee as the first animal model for Neisseria gonorrhoeae. They infected four male chimpanzees with human urethral exudates containing N. gonorrhoeae. Brown, Lucas, and Kuhn (1972) infected a male chimpanzee with an in vitro inoculum of N. gonorrhoeae and established the venereal transmission of that infection from male to female chimpanzee. Sequential serum samples were obtained from these six infected chimpanzees and tested for gonococcal antibody by a variety of serological assays.